Article Version of Record

A tutorial for joint modeling of longitudinal and time-to-event data in R

Author(s) / Creator(s)

Cekic, Sezen
Aichele, Stephen
Brandmaier, Andreas M.
Köhncke, Ylva
Ghisletta, Paolo

Abstract / Description

In biostatistics and medical research, longitudinal data are often composed of repeated assessments of a variable and dichotomous indicators to mark an event of interest. Consequently, joint modeling of longitudinal and time-to-event data has generated much interest in these disciplines over the previous decade. In behavioural sciences, too, often we are interested in relating individual trajectories and discrete events. Yet, joint modeling is rarely applied in behavioural sciences more generally. This tutorial presents an overview and general framework for joint modeling of longitudinal and time-to-event data, and fully illustrates its application in the context of a behavioral study with the JMbayes R package. In particular, the tutorial discusses practical topics, such as model selection and comparison, choice of joint modeling parameterization and interpretation of model parameters. In the end, this tutorial aims at introducing didactically the theory related to joint modeling and to introduce novice analysts to the use of the JMbayes package.

Keyword(s)

tutorial joint model mixed-effects model time-to-event association structures JMbayes package application

Persistent Identifier

Date of first publication

2021-05-11

Journal title

Quantitative and Computational Methods in Behavioral Sciences

Volume

1

Article number

Article e2979

Publisher

PsychOpen GOLD

Publication status

publishedVersion

Review status

peerReviewed

Is version of

Citation

Cekic, S., Aichele, S., Brandmaier, A. M., Köhncke, Y., & Ghisletta, P. (2021). A tutorial for joint modeling of longitudinal and time-to-event data in R. Quantitative and Computational Methods in Behavioral Sciences, 1, Article e2979. https://doi.org/10.5964/qcmb.2979
  • Author(s) / Creator(s)
    Cekic, Sezen
  • Author(s) / Creator(s)
    Aichele, Stephen
  • Author(s) / Creator(s)
    Brandmaier, Andreas M.
  • Author(s) / Creator(s)
    Köhncke, Ylva
  • Author(s) / Creator(s)
    Ghisletta, Paolo
  • PsychArchives acquisition timestamp
    2022-04-14T11:25:26Z
  • Made available on
    2022-04-14T11:25:26Z
  • Date of first publication
    2021-05-11
  • Abstract / Description
    In biostatistics and medical research, longitudinal data are often composed of repeated assessments of a variable and dichotomous indicators to mark an event of interest. Consequently, joint modeling of longitudinal and time-to-event data has generated much interest in these disciplines over the previous decade. In behavioural sciences, too, often we are interested in relating individual trajectories and discrete events. Yet, joint modeling is rarely applied in behavioural sciences more generally. This tutorial presents an overview and general framework for joint modeling of longitudinal and time-to-event data, and fully illustrates its application in the context of a behavioral study with the JMbayes R package. In particular, the tutorial discusses practical topics, such as model selection and comparison, choice of joint modeling parameterization and interpretation of model parameters. In the end, this tutorial aims at introducing didactically the theory related to joint modeling and to introduce novice analysts to the use of the JMbayes package.
    en_US
  • Publication status
    publishedVersion
  • Review status
    peerReviewed
  • Citation
    Cekic, S., Aichele, S., Brandmaier, A. M., Köhncke, Y., & Ghisletta, P. (2021). A tutorial for joint modeling of longitudinal and time-to-event data in R. Quantitative and Computational Methods in Behavioral Sciences, 1, Article e2979. https://doi.org/10.5964/qcmb.2979
    en_US
  • ISSN
    2699-8432
  • Persistent Identifier
    https://hdl.handle.net/20.500.12034/5739
  • Persistent Identifier
    https://doi.org/10.23668/psycharchives.6343
  • Language of content
    eng
  • Publisher
    PsychOpen GOLD
  • Is version of
    https://doi.org/10.5964/qcmb.2979
  • Is related to
    https://doi.org/10.23668/psycharchives.4772
  • Keyword(s)
    tutorial
    en_US
  • Keyword(s)
    joint model
    en_US
  • Keyword(s)
    mixed-effects model
    en_US
  • Keyword(s)
    time-to-event
    en_US
  • Keyword(s)
    association structures
    en_US
  • Keyword(s)
    JMbayes package
    en_US
  • Keyword(s)
    application
    en_US
  • Dewey Decimal Classification number(s)
    150
  • Title
    A tutorial for joint modeling of longitudinal and time-to-event data in R
    en_US
  • DRO type
    article
  • Article number
    Article e2979
  • Journal title
    Quantitative and Computational Methods in Behavioral Sciences
  • Volume
    1
  • Visible tag(s)
    Version of Record
    en_US