Article Version of Record

Quality of Life Following Liver Transplantation in Patients With Familial Amyloid Neuropathy: A Prospective Controlled Study

Author(s) / Creator(s)

Telles-Correia, Diogo
Barbosa, António
Mega, Inês
Monteiro, Estela
Barroso, Eduardo

Abstract / Description

Aim: The present study aimed to evaluate the change in quality of life 12 months following liver transplantation in patients with Familial Amyloid Polyneuropathy (FAP). Method: In this study 150 transplant candidates, attending the outpatient clinic of a Liver Transplantation Centre in Lisbon, were assessed between March 1, 2006 and December 1, 2007. From these, 84 were transplanted, and 62 finished the study; 20 with FAP and 42 with Liver Disease (LD). These patients were assessed before, and 12 months after, transplantation. The patients that remained waiting for transplantation originated the control group. First, transplanted (study group) and non-transplanted (control group) patients were compared regardless of their diagnosis, and then only FAP patients were compared between both groups. Results: 12 months after transplantation the score on the Quality of Life’s Physical and Mental Component of the SF-36 was significantly higher in transplanted versus non-transplanted patients (concerning the whole group FAP and LD patients). However, significant differences were only found for the Quality of Life’s Physical Component subscale between both FAP groups (study and control group). Conclusion: In sum, liver transplantation does not have a significant impact in FAP patients’ Mental Quality of Life score. One possible reason to this is the fail in acquiring adaptive coping strategies after transplantation.

Keyword(s)

liver transplantation familial amyloid polyneuropathy quality of life mental health coping

Persistent Identifier

Date of first publication

2014-07-22

Journal title

Psychology, Community & Health

Volume

3

Issue

2

Page numbers

73–78

Publisher

PsychOpen GOLD

Publication status

publishedVersion

Review status

peerReviewed

Is version of

Citation

Telles-Correia, D., Barbosa, A., Mega, I., Monteiro, E., & Barroso, E. (2014). Quality of Life Following Liver Transplantation in Patients With Familial Amyloid Neuropathy: A Prospective Controlled Study. Psychology, Community & Health, 3(2), 73–78. https://doi.org/10.5964/pch.v3i2.60
  • Author(s) / Creator(s)
    Telles-Correia, Diogo
  • Author(s) / Creator(s)
    Barbosa, António
  • Author(s) / Creator(s)
    Mega, Inês
  • Author(s) / Creator(s)
    Monteiro, Estela
  • Author(s) / Creator(s)
    Barroso, Eduardo
  • PsychArchives acquisition timestamp
    2018-12-06T06:49:04Z
  • Made available on
    2018-12-06T06:49:04Z
  • Date of first publication
    2014-07-22
  • Abstract / Description
    Aim: The present study aimed to evaluate the change in quality of life 12 months following liver transplantation in patients with Familial Amyloid Polyneuropathy (FAP). Method: In this study 150 transplant candidates, attending the outpatient clinic of a Liver Transplantation Centre in Lisbon, were assessed between March 1, 2006 and December 1, 2007. From these, 84 were transplanted, and 62 finished the study; 20 with FAP and 42 with Liver Disease (LD). These patients were assessed before, and 12 months after, transplantation. The patients that remained waiting for transplantation originated the control group. First, transplanted (study group) and non-transplanted (control group) patients were compared regardless of their diagnosis, and then only FAP patients were compared between both groups. Results: 12 months after transplantation the score on the Quality of Life’s Physical and Mental Component of the SF-36 was significantly higher in transplanted versus non-transplanted patients (concerning the whole group FAP and LD patients). However, significant differences were only found for the Quality of Life’s Physical Component subscale between both FAP groups (study and control group). Conclusion: In sum, liver transplantation does not have a significant impact in FAP patients’ Mental Quality of Life score. One possible reason to this is the fail in acquiring adaptive coping strategies after transplantation.
    en_US
  • Publication status
    publishedVersion
  • Review status
    peerReviewed
  • Citation
    Telles-Correia, D., Barbosa, A., Mega, I., Monteiro, E., & Barroso, E. (2014). Quality of Life Following Liver Transplantation in Patients With Familial Amyloid Neuropathy: A Prospective Controlled Study. Psychology, Community & Health, 3(2), 73–78. https://doi.org/10.5964/pch.v3i2.60
    en_US
  • ISSN
    2182-438X
  • Persistent Identifier
    https://hdl.handle.net/20.500.12034/1897
  • Persistent Identifier
    https://doi.org/10.23668/psycharchives.2263
  • Language of content
    eng
  • Publisher
    PsychOpen GOLD
  • Is version of
    https://doi.org/10.5964/pch.v3i2.60
  • Keyword(s)
    liver transplantation
    en_US
  • Keyword(s)
    familial amyloid polyneuropathy
    en_US
  • Keyword(s)
    quality of life
    en_US
  • Keyword(s)
    mental health
    en_US
  • Keyword(s)
    coping
    en_US
  • Dewey Decimal Classification number(s)
    150
  • Title
    Quality of Life Following Liver Transplantation in Patients With Familial Amyloid Neuropathy: A Prospective Controlled Study
    en_US
  • DRO type
    article
  • Issue
    2
  • Journal title
    Psychology, Community & Health
  • Page numbers
    73–78
  • Volume
    3
  • Visible tag(s)
    Version of Record